❗️Avian influenza, human – China (03): (GX) H10N3, patient recovery

Good and the bad, want to know what the future holds—read the ProMed report here.
• Patient Recovery: The first H10N3 avian influenza case in Guangxi, China, has recovered after over 40 days of treatment.
• Patient Demographics: The patient is a 23-year-old female with a BMI over 30, making her the youngest and most obese patient among the four reported H10N3 cases.
• Treatment Outcome: The patient’s successful treatment provides valuable experience for treating critical H10N3 cases in China.
• Patient’s Condition: Diagnosed with H10N3 avian influenza, severe pneumonia, respiratory failure, ARDS, mediastinal emphysema, and sepsis.
• Treatment Challenges: Patient’s weight posed difficulties for prone ventilation, requiring a team of 6-8 medical staff and careful ventilator parameter adjustments.
• Virus Transmission: H10N3 avian influenza virus, primarily transmitted among poultry, with only four human cases reported, all linked to direct or indirect contact with infected poultry.
• H10N3 Infection Case: A 23-year-old woman in Guangxi, China, contracted H10N3 avian influenza after visiting a market and touching poultry and birds.
• Severe Illness: The patient experienced severe symptoms, including fever, cough, pneumonia, respiratory failure, and sepsis, leading to a coma for over a month.
• Transmission and Pathogenicity: H10N3 avian influenza, typically low-pathogenic in poultry, can be transmitted to humans through droplets, causing severe respiratory complications.
• Source of Infection: The same virus was not detected in the poultry the patient came into contact with.
• Public Health Advice: Doctors advise the public not to panic but to practice good personal hygiene and avoid contact with live poultry.
• Global Situation: As of February 7, 2025, only four human cases of avian influenza A(H10N3) have been reported globally, with no sustained human-to-human transmission observed.
• Avian Influenza Outbreak: An outbreak of avian influenza has been reported in Guangxi Autonomous Region, China.
• Healthcare Response: The attending physicians of the Department of Respiratory and Critical Care Medicine at the Fourth People’s Hospital of Nanning are commended for their work.
• Prevention Efforts: The outbreak serves as a wake-up call for heightened prevention efforts at the community level.
• Donation Information: Details available at https://isid.networkforgood.com/projects/79924-invest-in-the-mission. • ProMED Website: https://www.promedmail.org/.
• Submission and Support: Submit items via the ProMED website and contact support via the same website.


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