Buruli-ulcer is a neglected tropical disease that is caused by the bacterium Mycobacterium ulcerans. The disease mainly affects the skin and soft tissues, causing painless, slow-healing ulcers that can lead to permanent disability if left untreated.

The disease is most prevalent in sub-Saharan Africa, although cases have been reported in other parts of the world, including Australia, South America, and Southeast Asia. Transmission of the disease is not well understood, but it is thought to be spread through contact with contaminated water or soil.

Diagnosis of Buruli-ulcer can be challenging, as it often resembles other skin conditions. Treatment typically involves a combination of antibiotics and surgery, with early detection increasing the chances of a successful outcome.

Prevention measures for the disease include avoiding contact with contaminated water and soil, and promptly treating any cuts or wounds to prevent infection. Public health efforts are also critical to raising awareness of the disease and improving access to diagnosis and treatment.

Despite being classified as a neglected disease, the burden of Buruli-ulcer on affected communities is significant. It is for this reason that effective prevention, diagnosis, and treatment measures are urgently needed to address this debilitating condition.