PRO/AH/EDR> Dengue/DHF update (09): Asia (Bangladesh) DENV2 vs DENV3


A ProMED-mail post
ProMED-mail is a program of the
International Society for Infectious Diseases

[1] Date: Fri 11 Aug 2023
Source: Outbreak News Today [edited]

The Directorate General of Health Services (DGHS) in Dhaka, Bangladesh
reports 80 074 total dengue fever cases through 11 Aug 2023, with
cases nearly evenly split between the capital city of Dhaka and
outside of Dhaka.

2019 saw the most cases on record with 101 354 cases.

To date [11 Aug 2023], 373 dengue related fatalities have been
reported, nearly 100 deaths higher than the record year of 2022 when
281 deaths were reported for the whole year.

The World Health Organization reported in a DON today:

“Although dengue is endemic in Bangladesh, the current dengue surge is
unusual in terms of seasonality and the early sharp increase in
comparison to previous years, where the surge started around late
June. The CFR so far this year [2023] (0.47%) is relatively high
compared to previous years for the full-year period. The pre-monsoon
Aedes survey shows that the density of mosquitoes, and the number of
potential hotspots is at the highest level in the past 5 years.”

In addition, WHO discusses the circulating serotypes in the current

“DENV2 was the predominant circulating serotype in Bangladesh until
2018, when it was replaced by DENV3 as the predominant serotype since
2019. However, DENV2 has been identified as the primary circulating
serotype in this outbreak, and this may result in more severe dengue
infections and hospitalizations as a result of a 2nd infection with a
heterologous serotype. Of the 66 serotyped samples in the month of
June 2023, DENV2 (51.5%) and DENV3 (43.9%) were identified as the
circulating serotypes.”

Dengue is a disease caused by a virus spread through mosquito bites.
The disease can take up to 2 weeks to develop with illness generally
lasting less than a week.

Health effects from dengue include fever, headache, nausea, vomiting,
rash, muscle and joint pain, and minor bleeding.

Dengue can become severe within a few hours. Severe dengue is a
medical emergency, usually requiring hospitalization.

In severe cases, health effects can include hemorrhage (uncontrolled
bleeding), shock (seriously low blood pressure), organ failure, and

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